After the Women’s Health Initiative trial was halted (2002 for conjugated equine estrogen [CEE]-progestin arm) and (2004 for CEE only arm), women and all clinicians from around the globe avoided hormone replacement therapy. To be clear, the results from the WHI trial did not apply to younger women aged 50-60 or Yam based bio-identical hormones (BHRT). Furthermore, many of the women who were studied in the trial were 65 years or older with pre-existing heart disease and other co-morbidities. The most harm was found with the addition of synthetic progestin (MPA or Provera).
In menopause, the loss of estrogen can lead to serious health problems including osteoporosis and hip fractures, urogenital atrophy, Alzheimer’s disease, depression, macular degeneration, sleep disturbances, sexual dysfunction, cancer and death. Dr. Jennifer Blake, CEO of the Society of Obstetricians and Gynecologists of Canada (SOGC), noted a study published in 2013 that an estimated 91,610 American women died prematurely between 2002 and 2012 as a result of avoiding estrogen therapy. Four other studies and meta-analyses show protective benefits using estrogen particularly on cognition, dementia, and coronary artery disease.
Bio-identical hormones are natural hormones where the chemical structure compounds are identical to the structure of hormones produced by the human body. Hormones are preventative medicine and can greatly improve your quality of life.